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==Solution structure of the FF Domain 2 of human transcription elongation factor CA150==
==Solution structure of the FF Domain 2 of human transcription elongation factor CA150==
<StructureSection load='2kiq' size='340' side='right'caption='[[2kiq]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2kiq' size='340' side='right'caption='[[2kiq]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2kiq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KIQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KIQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2kiq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KIQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KIQ FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TCERG1, CA150, TAF2S ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kiq OCA], [https://pdbe.org/2kiq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kiq RCSB], [https://www.ebi.ac.uk/pdbsum/2kiq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kiq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kiq OCA], [https://pdbe.org/2kiq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kiq RCSB], [https://www.ebi.ac.uk/pdbsum/2kiq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kiq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/TCRG1_HUMAN TCRG1_HUMAN]] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.<ref>PMID:9315662</ref> <ref>PMID:11604498</ref>
[https://www.uniprot.org/uniprot/TCRG1_HUMAN TCRG1_HUMAN] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.<ref>PMID:9315662</ref> <ref>PMID:11604498</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Boyles, J]]
[[Category: Boyles J]]
[[Category: Donald, B R]]
[[Category: Donald BR]]
[[Category: Tripathy, C]]
[[Category: Tripathy C]]
[[Category: Yan, A]]
[[Category: Yan A]]
[[Category: Zeng, J]]
[[Category: Zeng J]]
[[Category: Zhou, P]]
[[Category: Zhou P]]
[[Category: Activator]]
[[Category: Alternative splicing]]
[[Category: Coiled coil]]
[[Category: Ff domain]]
[[Category: Human transcription elongation factor ca150]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Repressor]]
[[Category: Residual dipolar coupling]]
[[Category: Rna polymerase ii c-terminal domain interacting protein]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulator]]
Retrieved from "https://proteopedia.org/2kiq"