7nee: Difference between revisions

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<StructureSection load='7nee' size='340' side='right'caption='[[7nee]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='7nee' size='340' side='right'caption='[[7nee]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7nee]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NEE FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NEE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=U9B:(1R,3S)-3-(4-ammoniobutyl)-1-benzyl-1,4-azaphosphinan-1-ium-3-carboxylate+4,4-dioxide'>U9B</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CPB2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=U9B:(1R,3S)-3-(4-ammoniobutyl)-1-benzyl-1,4-azaphosphinan-1-ium-3-carboxylate+4,4-dioxide'>U9B</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Carboxypeptidase_U Carboxypeptidase U], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.20 3.4.17.20] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nee OCA], [https://pdbe.org/7nee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nee RCSB], [https://www.ebi.ac.uk/pdbsum/7nee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nee ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nee OCA], [https://pdbe.org/7nee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nee RCSB], [https://www.ebi.ac.uk/pdbsum/7nee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nee ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/CBPB2_HUMAN CBPB2_HUMAN]] Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.<ref>PMID:10574983</ref> 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7nee" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7nee" style="background-color:#fffaf0;"></div>
==See Also==
*[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Carboxypeptidase U]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Brown, D G]]
[[Category: Brown DG]]
[[Category: Gloanec, P]]
[[Category: Gloanec P]]
[[Category: Raimbaud, E]]
[[Category: Raimbaud E]]
[[Category: Schaffner, A P]]
[[Category: Schaffner AP]]
[[Category: Vuillard, L M]]
[[Category: Vuillard LM]]
[[Category: Complex]]
[[Category: Hydrolase]]
[[Category: Inhibitor]]

Latest revision as of 06:35, 21 November 2024

Inhibitor Complex with Thrombin Activatable Fibrinolysis inhibitor (TAFIa)

7nee, resolution 2.55Å

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