Sandbox GGC16: Difference between revisions
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Myeloid Leukemia. Blood. 2003, 101(5), 2074–2074.</ref> It is highly polar due to the abundance of proline, glutamate, serine, and threonine. Proteins with a PEST region typically have a short half-life of under 2 hours. It is believed that the PEST region is a tag for fast degradation of the protein. This mutation likely provides a mechanism for the protein to evade degradation, enabling it to continue inducing transcription. This could contribute to cancerous growth of white blood cells. | Myeloid Leukemia. Blood. 2003, 101(5), 2074–2074.</ref> It is highly polar due to the abundance of proline, glutamate, serine, and threonine. Proteins with a PEST region typically have a short half-life of under 2 hours. It is believed that the PEST region is a tag for fast degradation of the protein. This mutation likely provides a mechanism for the protein to evade degradation, enabling it to continue inducing transcription. This could contribute to cancerous growth of white blood cells. | ||
== References == | == References == | ||
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