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New page: '''Unreleased structure''' The entry 7ocb is ON HOLD Authors: Johansson, C., Krojer, T., Park, K., Xiong, Y., Jin, J., Oppermann, U. Description: Crystal structure of Spindlin1 in comp...
 
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'''Unreleased structure'''


The entry 7ocb is ON HOLD
==Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B==
<StructureSection load='7ocb' size='340' side='right'caption='[[7ocb]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7ocb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OCB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=V88:7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-2N-[2-(dimethylamino)ethyl]-6-methoxy-4N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamine'>V88</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ocb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ocb OCA], [https://pdbe.org/7ocb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ocb RCSB], [https://www.ebi.ac.uk/pdbsum/7ocb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ocb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).


Authors: Johansson, C., Krojer, T., Park, K., Xiong, Y., Jin, J., Oppermann, U.
==See Also==
 
*[[Spindlin|Spindlin]]
Description: Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Oppermann, U]]
[[Category: Homo sapiens]]
[[Category: Park, K]]
[[Category: Large Structures]]
[[Category: Xiong, Y]]
[[Category: Jin J]]
[[Category: Johansson, C]]
[[Category: Johansson C]]
[[Category: Krojer, T]]
[[Category: Krojer T]]
[[Category: Jin, J]]
[[Category: Oppermann U]]
[[Category: Park K]]
[[Category: Xiong Y]]
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