2ajx: Difference between revisions

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<StructureSection load='2ajx' size='340' side='right'caption='[[2ajx]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='2ajx' size='340' side='right'caption='[[2ajx]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ajx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AJX FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ajx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AJX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TGN:3-(HYDROXY-PHENYL-PHOSPHINOYLOXY)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC+ACID+METHYL+ESTER'>TGN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ajs|2ajs]], [[2aju|2aju]], [[2ajv|2ajv]], [[2ajy|2ajy]], [[2ajz|2ajz]], [[2ak1|2ak1]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TGN:3-(HYDROXY-PHENYL-PHOSPHINOYLOXY)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC+ACID+METHYL+ESTER'>TGN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ajx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ajx OCA], [https://pdbe.org/2ajx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ajx RCSB], [https://www.ebi.ac.uk/pdbsum/2ajx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ajx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ajx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ajx OCA], [https://pdbe.org/2ajx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ajx RCSB], [https://www.ebi.ac.uk/pdbsum/2ajx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ajx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IGKC_MOUSE IGKC_MOUSE]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aj/2ajx_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aj/2ajx_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Wilson, I A]]
[[Category: Wilson IA]]
[[Category: Zhu, X]]
[[Category: Zhu X]]
[[Category: Catalytic antibody]]
[[Category: Fab]]
[[Category: Hydrolytic]]
[[Category: Immune system]]
[[Category: Transition state analog]]

Latest revision as of 07:34, 9 October 2024

Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with Transition State Analog

2ajx, resolution 1.85Å

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