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==Solution structure of the C-terminal Pdr1-activating domain of the J-protein Zuo1==
==Solution structure of the C-terminal Pdr1-activating domain of the J-protein Zuo1==
<StructureSection load='2lwx' size='340' side='right'caption='[[2lwx]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2lwx' size='340' side='right'caption='[[2lwx]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2lwx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LWX FirstGlance]. <br>
<table><tr><td colspan='2'>[[2lwx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LWX FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YGR285C, ZUO1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwx OCA], [https://pdbe.org/2lwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lwx RCSB], [https://www.ebi.ac.uk/pdbsum/2lwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lwx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwx OCA], [https://pdbe.org/2lwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lwx RCSB], [https://www.ebi.ac.uk/pdbsum/2lwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lwx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ZUO1_YEAST ZUO1_YEAST]] Component of the ribosome-associated complex (RAC), a heterodimeric chaperone complex involved in regulation of accurate translation termination and in folding or maintaining nascent polypeptides in a folding-competent state. RAC stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones SSB1/SSB2 that bind to the nascent polypeptide chain. ZUO1 can act as a J-protein for SSB1/SSB2 only when associated with SSZ1.<ref>PMID:15456889</ref> <ref>PMID:15908962</ref>
[https://www.uniprot.org/uniprot/ZUO1_YEAST ZUO1_YEAST] Component of the ribosome-associated complex (RAC), a heterodimeric chaperone complex involved in regulation of accurate translation termination and in folding or maintaining nascent polypeptides in a folding-competent state. RAC stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones SSB1/SSB2 that bind to the nascent polypeptide chain. ZUO1 can act as a J-protein for SSB1/SSB2 only when associated with SSZ1.<ref>PMID:15456889</ref> <ref>PMID:15908962</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Craig, E A]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Ducett, J K]]
[[Category: Craig EA]]
[[Category: Peterson, F C]]
[[Category: Ducett JK]]
[[Category: Volkman, B F]]
[[Category: Peterson FC]]
[[Category: Chaperone]]
[[Category: Volkman BF]]
[[Category: J-protein]]
[[Category: Molecular chaperone]]
[[Category: Pleiotropic drug resistance]]
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