7byi: Difference between revisions
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==Structure of SHMT2 in complex with CBX== | |||
<StructureSection load='7byi' size='340' side='right'caption='[[7byi]], [[Resolution|resolution]] 2.76Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7byi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BYI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BYI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.76Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBO:CARBENOXOLONE'>CBO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7byi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7byi OCA], [https://pdbe.org/7byi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7byi RCSB], [https://www.ebi.ac.uk/pdbsum/7byi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7byi ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GLYM_HUMAN GLYM_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.<ref>PMID:21876188</ref> | |||
==See Also== | |||
*[[Serine hydroxymethyltransferase 3D structures|Serine hydroxymethyltransferase 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: Chen | </StructureSection> | ||
[[Category: Li | [[Category: Homo sapiens]] | ||
[[Category: Lu | [[Category: Large Structures]] | ||
[[Category: Zhang | [[Category: Chen Y]] | ||
[[Category: Li L]] | |||
[[Category: Lu D]] | |||
[[Category: Su D]] | |||
[[Category: Zhang C]] | |||
Latest revision as of 15:41, 29 November 2023
Structure of SHMT2 in complex with CBX
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