7kh0: Difference between revisions
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==== | ==Cryo-EM structure of the human arginine vasopressin AVP-vasopressin receptor V2R-Gs signaling complex== | ||
<StructureSection load='7kh0' size='340' side='right'caption='[[7kh0]]' scene=''> | <StructureSection load='7kh0' size='340' side='right'caption='[[7kh0]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7kh0]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KH0 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kh0 OCA], [https://pdbe.org/7kh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kh0 RCSB], [https://www.ebi.ac.uk/pdbsum/7kh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kh0 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kh0 OCA], [https://pdbe.org/7kh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kh0 RCSB], [https://www.ebi.ac.uk/pdbsum/7kh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kh0 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/V2R_HUMAN V2R_HUMAN] Nephrogenic syndrome of inappropriate antidiuresis;Inappropriate antidiuretic hormone secretion syndrome;Nephrogenic diabetes insipidus. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/V2R_HUMAN V2R_HUMAN] Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.<ref>PMID:19440390</ref> | |||
==See Also== | |||
*[[Transducin 3D structures|Transducin 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Lama glama]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Z | [[Category: Du Y]] | ||
[[Category: Gao S]] | |||
[[Category: Liu H]] | |||
[[Category: Liu Z]] | |||
[[Category: Sun D]] | |||
[[Category: Wang L]] | |||
[[Category: Xu J]] | |||
[[Category: Zhang C]] | |||
Latest revision as of 11:05, 23 October 2024
Cryo-EM structure of the human arginine vasopressin AVP-vasopressin receptor V2R-Gs signaling complex
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