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==The NMR structure of the rubredoxin domain of the NO Reductase Flavorubredoxin from Escherichia coli==
==The NMR structure of the rubredoxin domain of the NO Reductase Flavorubredoxin from Escherichia coli==
<StructureSection load='2ms3' size='340' side='right'caption='[[2ms3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2ms3' size='340' side='right'caption='[[2ms3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ms3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MS3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ms3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MS3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">norV, flrD, ygaI, ygaJ, ygaK, b2710, JW2680 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ms3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms3 OCA], [https://pdbe.org/2ms3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ms3 RCSB], [https://www.ebi.ac.uk/pdbsum/2ms3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ms3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms3 OCA], [https://pdbe.org/2ms3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ms3 RCSB], [https://www.ebi.ac.uk/pdbsum/2ms3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/NORV_ECOLI NORV_ECOLI]] Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the reductase at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase.<ref>PMID:11751865</ref> <ref>PMID:12101220</ref>
[https://www.uniprot.org/uniprot/NORV_ECOLI NORV_ECOLI] Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the reductase at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase.<ref>PMID:11751865</ref> <ref>PMID:12101220</ref>  
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lamosa, P M]]
[[Category: Lamosa PM]]
[[Category: Silva, E]]
[[Category: Silva E]]
[[Category: Teixeira, M]]
[[Category: Teixeira M]]
[[Category: Turner, D L]]
[[Category: Turner DL]]
[[Category: Electron transport]]
[[Category: Flavorubredoxin]]
[[Category: Nitric oxide]]
[[Category: Nitric oxide reductase]]
[[Category: Norv]]
[[Category: Rubredoxin]]

Latest revision as of 07:02, 1 May 2024

The NMR structure of the rubredoxin domain of the NO Reductase Flavorubredoxin from Escherichia coli

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