2n3b: Difference between revisions
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==Structure of oxidized horse heart cytochrome c encapsulated in reverse micelles== | ==Structure of oxidized horse heart cytochrome c encapsulated in reverse micelles== | ||
<StructureSection load='2n3b' size='340' side='right'caption='[[2n3b | <StructureSection load='2n3b' size='340' side='right'caption='[[2n3b]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2n3b]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N3B FirstGlance]. <br> | <table><tr><td colspan='2'>[[2n3b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N3B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N3B FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, models</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n3b OCA], [https://pdbe.org/2n3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n3b RCSB], [https://www.ebi.ac.uk/pdbsum/2n3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n3b ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n3b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n3b OCA], [https://pdbe.org/2n3b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n3b RCSB], [https://www.ebi.ac.uk/pdbsum/2n3b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n3b ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CYC_HORSE CYC_HORSE] Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity). | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Equus caballus]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Fuglestad B]] | ||
[[Category: | [[Category: Nucci NV]] | ||
[[Category: | [[Category: O'Brien ES]] | ||
[[Category: Tommos | [[Category: Tommos C]] | ||
[[Category: Wand | [[Category: Wand A]] | ||
