2iu7: Difference between revisions
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New page: left|200px<br /> <applet load="2iu7" size="450" color="white" frame="true" align="right" spinBox="true" caption="2iu7, resolution 1.91Å" /> '''SITE DIRECTED MUTAG... |
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== | ==Site directed mutagenesis of key residues involved in the catalytic mechanism of Cyanase== | ||
<StructureSection load='2iu7' size='340' side='right'caption='[[2iu7]], [[Resolution|resolution]] 1.91Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2iu7]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IU7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IU7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iu7 OCA], [https://pdbe.org/2iu7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iu7 RCSB], [https://www.ebi.ac.uk/pdbsum/2iu7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iu7 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CYNS_ECOLI CYNS_ECOLI] Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iu/2iu7_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iu7 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Anderson | [[Category: Anderson PM]] | ||
[[Category: Guilloton | [[Category: Guilloton M]] | ||
[[Category: Joachimiak | [[Category: Joachimiak A]] | ||
[[Category: Walsh | [[Category: Walsh MA]] | ||
Latest revision as of 14:25, 13 December 2023
Site directed mutagenesis of key residues involved in the catalytic mechanism of Cyanase
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