2ofz: Difference between revisions
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<StructureSection load='2ofz' size='340' side='right'caption='[[2ofz]], [[Resolution|resolution]] 1.17Å' scene=''> | <StructureSection load='2ofz' size='340' side='right'caption='[[2ofz]], [[Resolution|resolution]] 1.17Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ofz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2ofz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/SARS_coronavirus_Tor2 SARS coronavirus Tor2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OFZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OFZ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.17Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ofz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ofz OCA], [https://pdbe.org/2ofz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ofz RCSB], [https://www.ebi.ac.uk/pdbsum/2ofz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ofz ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ofz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ofz OCA], [https://pdbe.org/2ofz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ofz RCSB], [https://www.ebi.ac.uk/pdbsum/2ofz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ofz ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/NCAP_SARS NCAP_SARS] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication (PubMed:17210170). May modulate transforming growth factor-beta signaling by binding host SMAD3 (PubMed:18055455).[HAMAP-Rule:MF_04096]<ref>PMID:17210170</ref> <ref>PMID:18055455</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Buchmeier | [[Category: SARS coronavirus Tor2]] | ||
[[Category: Joseph | [[Category: Buchmeier M]] | ||
[[Category: Kuhn | [[Category: Joseph J]] | ||
[[Category: Neuman | [[Category: Kuhn P]] | ||
[[Category: Saikatendu | [[Category: Neuman B]] | ||
[[Category: Stevens | [[Category: Saikatendu K]] | ||
[[Category: Subramanian | [[Category: Stevens RC]] | ||
[[Category: Subramanian V]] | |||