2oz6: Difference between revisions

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<StructureSection load='2oz6' size='340' side='right'caption='[[2oz6]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='2oz6' size='340' side='right'caption='[[2oz6]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2oz6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OZ6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2oz6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OZ6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vfr ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oz6 OCA], [https://pdbe.org/2oz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oz6 RCSB], [https://www.ebi.ac.uk/pdbsum/2oz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oz6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oz6 OCA], [https://pdbe.org/2oz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oz6 RCSB], [https://www.ebi.ac.uk/pdbsum/2oz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oz6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/VFR_PSEAE VFR_PSEAE]] Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.  
[https://www.uniprot.org/uniprot/VFR_PSEAE VFR_PSEAE] Can bind cyclic AMP. Is a global regulator of virulence factor expression and is required for exotoxin A and protease production.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bright, A R]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Cordes, T J]]
[[Category: Bright AR]]
[[Category: Forest, K T]]
[[Category: Cordes TJ]]
[[Category: Camp receptor protein]]
[[Category: Forest KT]]
[[Category: Camp-binding protein]]
[[Category: Dna binding protein]]
[[Category: Dna-binding protein]]
[[Category: Helix-turn-helix]]
[[Category: Nucleotide binding protein]]
[[Category: Transcription factor]]
[[Category: Winged helix]]

Latest revision as of 10:51, 30 August 2023

Crystal Structure of Virulence Factor Regulator from Pseudomonas aeruginosa in complex with cAMP

2oz6, resolution 2.80Å

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