7f3k: Difference between revisions
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New page: '''Unreleased structure''' The entry 7f3k is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Crystal structure of human YBX2 CSD in complex with m5C RNA in space group P21212== | |||
<StructureSection load='7f3k' size='340' side='right'caption='[[7f3k]], [[Resolution|resolution]] 1.76Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7f3k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7F3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7F3K FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7f3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7f3k OCA], [https://pdbe.org/7f3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7f3k RCSB], [https://www.ebi.ac.uk/pdbsum/7f3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7f3k ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/YBOX2_HUMAN YBOX2_HUMAN] Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full-length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay (By similarity).[UniProtKB:Q9Z2C8] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Huang Y]] | |||
[[Category: Zhang Y]] | |||
Latest revision as of 17:08, 29 November 2023
Crystal structure of human YBX2 CSD in complex with m5C RNA in space group P21212
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