7owv: Difference between revisions

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New page: '''Unreleased structure''' The entry 7owv is ON HOLD until Paper Publication Authors: Gardonyi, M., Heine, A., Klebe, G. Description: Crystal structure of IpgC in complex with a follow...
 
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'''Unreleased structure'''


The entry 7owv is ON HOLD  until Paper Publication
==Crystal structure of IpgC in complex with a follow-up compound based on J20==
 
<StructureSection load='7owv' size='340' side='right'caption='[[7owv]], [[Resolution|resolution]] 1.59&Aring;' scene=''>
Authors: Gardonyi, M., Heine, A., Klebe, G.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7owv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OWV FirstGlance]. <br>
Description: Crystal structure of IpgC in complex with a follow-up compound based on J20
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2IY:3-(4-chlorophenyl)-5-methylsulfanyl-1~{H}-pyrazole-4-carbonitrile'>2IY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
[[Category: Gardonyi, M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7owv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7owv OCA], [https://pdbe.org/7owv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7owv RCSB], [https://www.ebi.ac.uk/pdbsum/7owv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7owv ProSAT]</span></td></tr>
[[Category: Heine, A]]
</table>
[[Category: Klebe, G]]
== Function ==
[https://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Shigella flexneri]]
[[Category: Gardonyi M]]
[[Category: Heine A]]
[[Category: Klebe G]]
Retrieved from "https://proteopedia.org/7owv"