7p33: Difference between revisions
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New page: '''Unreleased structure''' The entry 7p33 is ON HOLD Authors: Suraweera, C.D., Hinds, M.G., Kvansakul, M. Description: Epstein-Barr virus encoded Bcl-2 homolog BHRF-1 in complex with B... |
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==Epstein-Barr virus encoded Bcl-2 homolog BHRF-1 in complex with Bid BH3 peptide== | |||
<StructureSection load='7p33' size='340' side='right'caption='[[7p33]], [[Resolution|resolution]] 2.79Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7p33]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_herpesvirus_4_strain_B95-8 Human herpesvirus 4 strain B95-8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P33 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P33 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7854273Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p33 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p33 OCA], [https://pdbe.org/7p33 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p33 RCSB], [https://www.ebi.ac.uk/pdbsum/7p33 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p33 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Hinds | == Function == | ||
[https://www.uniprot.org/uniprot/EAR_EBVB9 EAR_EBVB9] Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic proteins to prevent mitochondria permeabilization, release of cytochrome c and subsequent apoptosis of the host cell. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Human herpesvirus 4 strain B95-8]] | |||
[[Category: Large Structures]] | |||
[[Category: Hinds MG]] | |||
[[Category: Kvansakul M]] | |||
[[Category: Suraweera CD]] | |||
Latest revision as of 13:00, 1 February 2024
Epstein-Barr virus encoded Bcl-2 homolog BHRF-1 in complex with Bid BH3 peptide
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