1jan: Difference between revisions

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<StructureSection load='1jan' size='340' side='right'caption='[[1jan]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='1jan' size='340' side='right'caption='[[1jan]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1jan]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JAN FirstGlance]. <br>
<table><tr><td colspan='2'>[[1jan]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JAN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HOA:HYDROXYAMINE'>HOA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Neutrophil_collagenase Neutrophil collagenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.34 3.4.24.34] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jan OCA], [https://pdbe.org/1jan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jan RCSB], [https://www.ebi.ac.uk/pdbsum/1jan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jan ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jan OCA], [https://pdbe.org/1jan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jan RCSB], [https://www.ebi.ac.uk/pdbsum/1jan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jan ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MMP8_HUMAN MMP8_HUMAN]] Can degrade fibrillar type I, II, and III collagens.  
[https://www.uniprot.org/uniprot/MMP8_HUMAN MMP8_HUMAN] Can degrade fibrillar type I, II, and III collagens.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Neutrophil collagenase]]
[[Category: Bode W]]
[[Category: Bode, W]]
[[Category: Grams F]]
[[Category: Grams, F]]
[[Category: Huber R]]
[[Category: Huber, R]]
[[Category: Kleine T]]
[[Category: Kleine, T]]
[[Category: Pieper M]]
[[Category: Pieper, M]]
[[Category: Reinemer P]]
[[Category: Reinemer, P]]
[[Category: Schnierer S]]
[[Category: Schnierer, S]]
[[Category: Tschesche H]]
[[Category: Tschesche, H]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Metalloprotease]]
[[Category: Metzincin]]
[[Category: Zinc-endopeptidase]]