7phm: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 7phm is ~~ON HOLD~~

==Cryo-EM structure of Mycobacterium tuberculosis encapsulin==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[7phm]] is a 60 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PHM FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.2Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7phm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7phm OCA], [https://pdbe.org/7phm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7phm RCSB], [https://www.ebi.ac.uk/pdbsum/7phm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7phm ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/ENCAP_MYCTU ENCAP_MYCTU] Shell component of a type 1 encapsulin nanocompartment in situ; its cargo protects against oxidative stress at low pH. In situ and in E.coli assembles into proteinaceous shells about 22 nm in diameter with 2.5 nm thick walls (PubMed:24855650, PubMed:34751132). Cargo proteins are targeted to the interior via their C-terminal extensions; empty intact shells can be isolated in E.coli in the absence of cargo protein. There are at least 4 possible cargo proteins, DyP (encoded in the same locus), FolB, BfrB and Rv1762c; DyP and Rv1762c have been identified in vivo (PubMed:24855650). Probably involved in protection against oxidative damage from the host immune response (Probable) (PubMed:34751132). A T-cell antigen found in bacterial culture cell filtrates, stimulates mouse immune response. Does not have detectable bacteriocin activity (PubMed:9596740).<ref>PMID:24855650</ref> <ref>PMID:34751132</ref> <ref>PMID:9596740</ref> <ref>PMID:24855650</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Mycobacterium tuberculosis H37Rv]]

[[Category: Woodward JD]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7phm is ON HOLD
+==Cryo-EM structure of Mycobacterium tuberculosis encapsulin==
+<StructureSection load='7phm' size='340' side='right'caption='[[7phm]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7phm]] is a 60 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PHM FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7phm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7phm OCA], [https://pdbe.org/7phm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7phm RCSB], [https://www.ebi.ac.uk/pdbsum/7phm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7phm ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ENCAP_MYCTU ENCAP_MYCTU] Shell component of a type 1 encapsulin nanocompartment in situ; its cargo protects against oxidative stress at low pH. In situ and in E.coli assembles into proteinaceous shells about 22 nm in diameter with 2.5 nm thick walls (PubMed:24855650, PubMed:34751132). Cargo proteins are targeted to the interior via their C-terminal extensions; empty intact shells can be isolated in E.coli in the absence of cargo protein. There are at least 4 possible cargo proteins, DyP (encoded in the same locus), FolB, BfrB and Rv1762c; DyP and Rv1762c have been identified in vivo (PubMed:24855650). Probably involved in protection against oxidative damage from the host immune response (Probable) (PubMed:34751132). A T-cell antigen found in bacterial culture cell filtrates, stimulates mouse immune response. Does not have detectable bacteriocin activity (PubMed:9596740).<ref>PMID:24855650</ref> <ref>PMID:34751132</ref> <ref>PMID:9596740</ref> <ref>PMID:24855650</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mycobacterium tuberculosis H37Rv]]
+[[Category: Woodward JD]]