7ru6: Difference between revisions
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New page: '''Unreleased structure''' The entry 7ru6 is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Cryo-EM structure of the HIV-1 restriction factor human SERINC3== | |||
<StructureSection load='7ru6' size='340' side='right'caption='[[7ru6]], [[Resolution|resolution]] 4.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7ru6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RU6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RU6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.4Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ru6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ru6 OCA], [https://pdbe.org/7ru6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ru6 RCSB], [https://www.ebi.ac.uk/pdbsum/7ru6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ru6 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SERC3_HUMAN SERC3_HUMAN] Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733, PubMed:26416734).<ref>PMID:26416733</ref> <ref>PMID:26416734</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Leonhardt SA]] | |||
[[Category: Purdy MD]] | |||
[[Category: Yeager M]] | |||
Latest revision as of 10:06, 6 September 2023
Cryo-EM structure of the HIV-1 restriction factor human SERINC3
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