1mjn: Difference between revisions

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<StructureSection load='1mjn' size='340' side='right'caption='[[1mjn]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='1mjn' size='340' side='right'caption='[[1mjn]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1mjn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MJN FirstGlance]. <br>
<table><tr><td colspan='2'>[[1mjn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MJN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mjn OCA], [https://pdbe.org/1mjn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mjn RCSB], [https://www.ebi.ac.uk/pdbsum/1mjn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mjn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mjn OCA], [https://pdbe.org/1mjn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mjn RCSB], [https://www.ebi.ac.uk/pdbsum/1mjn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mjn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN]] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.  
[https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mj/1mjn_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mj/1mjn_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Dong, Y C]]
[[Category: Dong YC]]
[[Category: Jun, C D]]
[[Category: Jun CD]]
[[Category: Liu, J H]]
[[Category: Liu JH]]
[[Category: McCormack, A]]
[[Category: McCormack A]]
[[Category: Shimaoka, M]]
[[Category: Shimaoka M]]
[[Category: Springer, T A]]
[[Category: Springer TA]]
[[Category: Wang, J H]]
[[Category: Wang JH]]
[[Category: Xiao, T]]
[[Category: Xiao T]]
[[Category: Yang, Y T]]
[[Category: Yang YT]]
[[Category: Zhang, R G]]
[[Category: Zhang RG]]
[[Category: Immune system]]
[[Category: Rossmann fold]]