1r16: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
 
(One intermediate revision by the same user not shown)
Line 3: Line 3:
<StructureSection load='1r16' size='340' side='right'caption='[[1r16]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1r16' size='340' side='right'caption='[[1r16]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1r16]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R16 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1r16]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R16 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N:ANY+5-MONOPHOSPHATE+NUCLEOTIDE'>N</scene>, <scene name='pdbligand=PYF:3-PYRIDINYLCARBINOL'>PYF</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1lbe|1lbe]], [[1ism|1ism]], [[1isj|1isj]], [[1isi|1isi]], [[1ish|1ish]], [[1isg|1isg]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N:ANY+5-MONOPHOSPHATE+NUCLEOTIDE'>N</scene>, <scene name='pdbligand=PYF:3-PYRIDINYLCARBINOL'>PYF</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r16 OCA], [https://pdbe.org/1r16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r16 RCSB], [https://www.ebi.ac.uk/pdbsum/1r16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r16 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r16 OCA], [https://pdbe.org/1r16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r16 RCSB], [https://www.ebi.ac.uk/pdbsum/1r16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r16 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/NADA_APLCA NADA_APLCA]] Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for calcium mobilization from endoplasmic reticulum. Also has cADPr hydrolase activity.<ref>PMID:11829748</ref>
[https://www.uniprot.org/uniprot/NADA_APLCA NADA_APLCA] Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for calcium mobilization from endoplasmic reticulum. Also has cADPr hydrolase activity.<ref>PMID:11829748</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 16: Line 15:
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/1r16_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/1r16_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
Line 37: Line 36:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aplca]]
[[Category: Aplysia californica]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Graeff, R]]
[[Category: Graeff R]]
[[Category: Hao, Q]]
[[Category: Hao Q]]
[[Category: Kriksunov, I A]]
[[Category: Kriksunov IA]]
[[Category: Lee, H C]]
[[Category: Lee HC]]
[[Category: Love, M L]]
[[Category: Love ML]]
[[Category: Munshi, C]]
[[Category: Munshi C]]
[[Category: Szebenyi, D M.E]]
[[Category: Szebenyi DME]]
[[Category: Thiel, D J]]
[[Category: Thiel DJ]]
[[Category: Adp-ribosyl cyclase]]
[[Category: Ca2+ signalling]]
[[Category: Cyclic adp-ribose]]
[[Category: Hydrolase]]
[[Category: Naadp]]

Latest revision as of 08:46, 6 November 2024

Aplysia ADP ribosyl cyclase with bound pyridylcarbinol and R5P

1r16, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1r16&oldid=4255407"