3D structures of hypoxia-inducible factor: Difference between revisions

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New page: ==3D structures of hypoxia-inducible factor== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *HIF-1α; Human domai...
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
*HIF-1α; Human domains – PAS-B 238-348; CTAD (C-terminal activation) 776-826;  
*HIF-1α; Human domains – PAS-B 238-348; CTAD (C-terminal activation) 776-826;  
**[[1l8c]] – hHIF-1 CTAD + CREB-binding protein – human – NMR<br />
**[[1l8c]] – hHIF-1 CTAD + CREB-binding protein – human – NMR<br />
**[[1h2k]], [[1h2l]], [[1h2m]], [[2ilm]], [[3d8c]] – hHIF-1 CTAD + FIH-1<br />
**[[1h2k]], [[1h2l]], [[1h2m]], [[2ilm]], [[3d8c]] – hHIF-1 CTAD + FIH-1<br />
**[[1l3e]] – hHIF-1 CTAD + P300<br />
**[[1l3e]] – hHIF-1 CTAD + P300<br />
**[[4zpr]] – hHIF-1  + ARNT + DNA<br />
**[[4zpr]] – hHIF-1  + ARNT + DNA<br />
**[[9of0]], [[9of2]], [[9ofu]] – hHIF-1 + ARNT + DNA – Cryo EM<br />
**[[4h6j]] – hHIF-1 PAS-B (mutant)  + ARNT <br />
**[[4h6j]] – hHIF-1 PAS-B (mutant)  + ARNT <br />
*HIF-1β or aryl hydrocarbon receptor nuclear translocator (ARNT); C-terminal PAS 345-470
*HIF-1β or aryl hydrocarbon receptor nuclear translocator (ARNT); C-terminal PAS 345-470
**[[2b02]], [[4eq1]] – hARNT PAS-B <br />
**[[2b02]], [[4eq1]] – hARNT PAS-B <br />
**[[1x0o]], [[2hv1]], [[2k7s]] – hARNT C-terminal PAS - NMR<br />
**[[1x0o]], [[2hv1]], [[2k7s]] – hARNT C-terminal PAS - NMR<br />
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**[[4pky]] – hARNT C-terminal PAS + HIF-2 peptide + ARNT-interacting protein<br />
**[[4pky]] – hARNT C-terminal PAS + HIF-2 peptide + ARNT-interacting protein<br />
**[[4lpz]] – hARNT C-terminal PAS + coactivator<br />
**[[4lpz]] – hARNT C-terminal PAS + coactivator<br />
**[[8g4a]] – hARNT C-terminal PAS + tetrazole derivative<br />
**[[8k71]], [[8k72]], [[8k73]] – hARNT C-terminal PAS + thiazole derivative<br />
**[[4gs9]] – hARNT C-terminal PAS (mutant) + HIF-2 peptide <br />
**[[4gs9]] – hARNT C-terminal PAS (mutant) + HIF-2 peptide <br />
**[[5tbm]] – hARNT C-terminal PAS + EPAS-1<br />
**[[5v0l]] – hARNT 70-345 + mAHR + DNA<br />
**[[4zp4]], [[4zpk]] – mARNT + mHIF-2 - mouse<br />
**[[4zp4]], [[4zpk]] – mARNT + mHIF-2 - mouse<br />
 
**[[7w80]] – mARNT + mHIF-2 + drug<br />
**[[5nj8]] – mARNT 85-345 + AHR + DNA<br />
**[[7vni]] – mARNT 85-345 + DmAHR <br />
**[[7v7l]], [[7v7w]] – mARNT + mHIF-3 <br />
**[[5sy5]] – mARNT + NPAS1<br />
**[[5sy7]] – mARNT + NPAS3 + DNA <br />
**[[7xhv]], [[7xi4]] – mARNT + NPAS4 + DNA <br />
*HIF-2α or endothelial PAS domain-containing protein  
*HIF-2α or endothelial PAS domain-containing protein  
**[[1p97]] – hHIF-2 C-terminal PAS - NMR<br />
**[[1p97]] – hHIF-2 C-terminal PAS - NMR<br />
**[[5kiz]] – hHIF-2 PAS-B – NMR<br />
**[[5kiz]] – hHIF-2 PAS-B – NMR<br />
**[[3f1n]], [[3f1o]], [[3h7w]], [[3h82]], [[4ghi]], [[3f1p]], [[6d0c]] – hHIF-2 PAS-B (mutant)  + ARNT <br />
**[[3f1n]], [[3f1o]], [[3f1p]], [[3h7w]], [[3h82]], [[4ghi]], [[6d0c]] – hHIF-2 PAS-B (mutant)  + ARNT <br />
**[[6czw]], [[6d09]], [[6d0b]], [[6x21]], [[6x28]], [[6x2h]], [[6x37]], [[6x3d]] – hHIF-2 PAS-B (mutant) + ARNT + inhibitor<br />
**[[6czw]], [[6d09]], [[6d0b]], [[6x21]], [[6x28]], [[6x2h]], [[6x37]], [[6x3d]] – hHIF-2 PAS-B (mutant) + ARNT + inhibitor<br />
**[[2a24]] – hHIF-2 PAS-B (mutant)  + ARNT C-terminal PAS - NMR<br />
**[[2a24]] – hHIF-2 PAS-B (mutant)  + ARNT C-terminal PAS - NMR<br />
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**[[4zqd]], [[6e3t]] – mHIF-2 + ARNT + inhibitor<br />
**[[4zqd]], [[6e3t]] – mHIF-2 + ARNT + inhibitor<br />
**[[6e3u]] – mHIF-2 (mutant)  + ARNT + agonist<br />
**[[6e3u]] – mHIF-2 (mutant)  + ARNT + agonist<br />
*HIF-3
**[[4wn5]] – hHIF-3 C-terminal PAS-B <br />
}}
}}
[[Category:Topic Page]]

Latest revision as of 09:42, 29 March 2026

3D structures of hypoxia-inducible factor

Updated on 29-March-2026

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Openfox

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