1v0p: Difference between revisions
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<StructureSection load='1v0p' size='340' side='right'caption='[[1v0p]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1v0p' size='340' side='right'caption='[[1v0p]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1v0p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1v0p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V0P FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PVB:PURVALANOL+B'>PVB</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v0p OCA], [https://pdbe.org/1v0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v0p RCSB], [https://www.ebi.ac.uk/pdbsum/1v0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v0p ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v0p OCA], [https://pdbe.org/1v0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v0p RCSB], [https://www.ebi.ac.uk/pdbsum/1v0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v0p ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CDK2H_PLAFK CDK2H_PLAFK] Serine/threonine-protein kinase (PubMed:8844681, PubMed:14604523). Involved in the control of the cell cycle (By similarity). Required for entry into S-phase and mitosis (By similarity). Probable component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). In schizonts, phosphorylates ORC1 resulting in its dissociation from DNA, relocalization to the cytoplasm and likely its degradation (By similarity).[UniProtKB:P04551]<ref>PMID:14604523</ref> <ref>PMID:8844681</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Plasmodium falciparum]] | ||
[[Category: Burgess | [[Category: Burgess D]] | ||
[[Category: Doerig | [[Category: Doerig C]] | ||
[[Category: Endicott | [[Category: Endicott J]] | ||
[[Category: Holton | [[Category: Holton S]] | ||
[[Category: Merckx | [[Category: Merckx A]] | ||
[[Category: Noble | [[Category: Noble M]] | ||
