3iss: Difference between revisions

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<StructureSection load='3iss' size='340' side='right'caption='[[3iss]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3iss' size='340' side='right'caption='[[3iss]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3iss]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ISS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ISS FirstGlance]. <br>
<table><tr><td colspan='2'>[[3iss]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ISS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ISS FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPU:URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL)+BUTYRIC+ACID'>EPU</scene>, <scene name='pdbligand=PO3:PHOSPHITE+ION'>PO3</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1a2n|1a2n]], [[1uae|1uae]], [[2z2c|2z2c]], [[1dlg|1dlg]], [[1eyn|1eyn]], [[1q3g|1q3g]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPU:URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL)+BUTYRIC+ACID'>EPU</scene>, <scene name='pdbligand=PO3:PHOSPHITE+ION'>PO3</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b3189, JW3156, murA, murZ ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_1-carboxyvinyltransferase UDP-N-acetylglucosamine 1-carboxyvinyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.7 2.5.1.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iss OCA], [https://pdbe.org/3iss PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iss RCSB], [https://www.ebi.ac.uk/pdbsum/3iss PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iss ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iss OCA], [https://pdbe.org/3iss PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iss RCSB], [https://www.ebi.ac.uk/pdbsum/3iss PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iss ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MURA_ECOLI MURA_ECOLI]] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.[HAMAP-Rule:MF_00111]  
[https://www.uniprot.org/uniprot/MURA_ECOLI MURA_ECOLI] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.[HAMAP-Rule:MF_00111]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]]
[[Category: Berti PJ]]
[[Category: Berti, P J]]
[[Category: Chindemi P]]
[[Category: Chindemi, P]]
[[Category: Jackson SG]]
[[Category: Jackson, S G]]
[[Category: Junop MS]]
[[Category: Junop, M S]]
[[Category: Zhang F]]
[[Category: Zhang, F]]
[[Category: Cell cycle]]
[[Category: Cell division]]
[[Category: Cell shape]]
[[Category: Cell wall biogenesis/degradation]]
[[Category: Peptidoglycan synthesis]]
[[Category: Protein-ligand]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/3iss"