2c1g: Difference between revisions

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<StructureSection load='2c1g' size='340' side='right'caption='[[2c1g]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='2c1g' size='340' side='right'caption='[[2c1g]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2c1g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Strr6 Strr6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C1G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C1G FirstGlance]. <br>
<table><tr><td colspan='2'>[[2c1g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C1G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C1G FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/N-acetylglucosamine_deacetylase N-acetylglucosamine deacetylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.33 3.5.1.33] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c1g OCA], [https://pdbe.org/2c1g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c1g RCSB], [https://www.ebi.ac.uk/pdbsum/2c1g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c1g ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c1g OCA], [https://pdbe.org/2c1g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c1g RCSB], [https://www.ebi.ac.uk/pdbsum/2c1g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c1g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PGDA_STRR6 PGDA_STRR6] Catalyzes the deacetylation of N-acetylglucosamine (GlcNAc) residues in peptidoglycan, a modification that confers host lysozyme resistance and contributes to pneumococcal virulence.<ref>PMID:10781617</ref> <ref>PMID:12438406</ref> <ref>PMID:16221761</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: N-acetylglucosamine deacetylase]]
[[Category: Streptococcus pneumoniae R6]]
[[Category: Strr6]]
[[Category: Blair DE]]
[[Category: Aalten, D M.F van]]
[[Category: MacRae JI]]
[[Category: Blair, D E]]
[[Category: Schuttelkopf AW]]
[[Category: MacRae, J I]]
[[Category: Van Aalten DMF]]
[[Category: Schuttelkopf, A W]]
[[Category: Carbohydrate esterase]]
[[Category: Ce-4]]
[[Category: Hydrolase]]
[[Category: Metalloenzyme]]
[[Category: Peptidoglycan deacetylase]]
Retrieved from "https://proteopedia.org/2c1g"