1i3p: Difference between revisions

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<StructureSection load='1i3p' size='340' side='right'caption='[[1i3p]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
<StructureSection load='1i3p' size='340' side='right'caption='[[1i3p]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1i3p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acmnpv Acmnpv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I3P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I3P FirstGlance]. <br>
<table><tr><td colspan='2'>[[1i3p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Autographa_californica_nucleopolyhedrovirus Autographa californica nucleopolyhedrovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I3P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I3P FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1p35|1p35]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">P35 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46015 AcMNPV])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i3p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i3p OCA], [https://pdbe.org/1i3p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i3p RCSB], [https://www.ebi.ac.uk/pdbsum/1i3p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i3p ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i3p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i3p OCA], [https://pdbe.org/1i3p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i3p RCSB], [https://www.ebi.ac.uk/pdbsum/1i3p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i3p ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/VP35_NPVAC VP35_NPVAC]] Blocks the insect or worm host cells apoptotic response initiated by the viral infection. Confers protection from cell death in mammalian cells. Acts by blocking the activity of members of the caspase family of proteases. Required for late and very late gene expression.  
[https://www.uniprot.org/uniprot/P35_NPVAC P35_NPVAC] Functions as an inhibitor of the host RNA interference antiviral response. Inhibits the insect host cell apoptotic response initiated by the viral infection. Blocks as well the activity of members of the caspase family of proteases. Required for late and very late gene expression.<ref>PMID:16081248</ref> <ref>PMID:1962198</ref> <ref>PMID:26018163</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Acmnpv]]
[[Category: Autographa californica nucleopolyhedrovirus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Cruz, W P.dela]]
[[Category: Fisher AJ]]
[[Category: Fisher, A J]]
[[Category: Friesen PD]]
[[Category: Friesen, P D]]
[[Category: Lemongello D]]
[[Category: Lemongello, D]]
[[Category: Dela Cruz WP]]
[[Category: Apoptosis]]
[[Category: Hairpin loop]]
[[Category: Helix-turn-helix]]
[[Category: Reactive site loop]]
Retrieved from "https://proteopedia.org/1i3p"