7vrm: Difference between revisions
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==crystal structure of BRD2-BD2 in complex with purine derivative== | |||
<StructureSection load='7vrm' size='340' side='right'caption='[[7vrm]], [[Resolution|resolution]] 1.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7vrm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VRM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VRM FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TEP:THEOPHYLLINE'>TEP</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vrm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vrm OCA], [https://pdbe.org/7vrm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vrm RCSB], [https://www.ebi.ac.uk/pdbsum/7vrm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vrm ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Ashok | == Function == | ||
[[Category: Deshmukh | [https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref> | ||
[[Category: | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arole A]] | |||
[[Category: Ashok S]] | |||
[[Category: Deshmukh P]] | |||
[[Category: Mathur S]] | |||
[[Category: Padmanabhan B]] | |||
Latest revision as of 11:08, 2 August 2023
crystal structure of BRD2-BD2 in complex with purine derivative
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