7q4l: Difference between revisions
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New page: '''Unreleased structure''' The entry 7q4l is ON HOLD Authors: Duszczyk, M.M., Allain, F.H.T. Description: The solution structure of hsDND1 RRM12 bound to CUUAUUUG RNA [[Category: Unrel... |
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The | ==The solution structure of hsDND1 RRM12 bound to CUUAUUUG RNA== | ||
<StructureSection load='7q4l' size='340' side='right'caption='[[7q4l]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7q4l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Q4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Q4L FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q4l OCA], [https://pdbe.org/7q4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q4l RCSB], [https://www.ebi.ac.uk/pdbsum/7q4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q4l ProSAT]</span></td></tr> | ||
[[Category: Allain | </table> | ||
[[Category: Duszczyk | == Function == | ||
[https://www.uniprot.org/uniprot/DND1_HUMAN DND1_HUMAN] RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity).<ref>PMID:18155131</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Allain FHT]] | |||
[[Category: Duszczyk MM]] | |||
Latest revision as of 06:16, 19 June 2024
The solution structure of hsDND1 RRM12 bound to CUUAUUUG RNA
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