7vug: Difference between revisions
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New page: '''Unreleased structure''' The entry 7vug is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Cryo-EM structure of a class A orphan GPCR in complex with Gi== | |||
<StructureSection load='7vug' size='340' side='right'caption='[[7vug]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7vug]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Niallia_circulans Niallia circulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VUG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7ZQ:3-chloranyl-~{N}-[2-oxidanylidene-2-[[(1~{S})-1-phenylethyl]amino]ethyl]benzamide'>7ZQ</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vug OCA], [https://pdbe.org/7vug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vug RCSB], [https://www.ebi.ac.uk/pdbsum/7vug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vug ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref> | |||
==See Also== | |||
*[[Transducin 3D structures|Transducin 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Niallia circulans]] | |||
[[Category: Hua T]] | |||
[[Category: Liu ZJ]] | |||
[[Category: Wu LJ]] | |||
[[Category: Zhou YL]] | |||
Latest revision as of 11:22, 18 June 2025
Cryo-EM structure of a class A orphan GPCR in complex with Gi
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