3hgt: Difference between revisions

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<StructureSection load='3hgt' size='340' side='right'caption='[[3hgt]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3hgt' size='340' side='right'caption='[[3hgt]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3hgt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HGT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HGT FirstGlance]. <br>
<table><tr><td colspan='2'>[[3hgt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HGT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HGT FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3hgq|3hgq]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HDA3, PLO1, YPR179C ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hgt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hgt OCA], [https://pdbe.org/3hgt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hgt RCSB], [https://www.ebi.ac.uk/pdbsum/3hgt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hgt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hgt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hgt OCA], [https://pdbe.org/3hgt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hgt RCSB], [https://www.ebi.ac.uk/pdbsum/3hgt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hgt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/HDA3_YEAST HDA3_YEAST]] Required for activity of HDA1 histone deacetylase complex. The HDA1 histone deacetylase complex is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.<ref>PMID:8663039</ref> <ref>PMID:11287668</ref>
[https://www.uniprot.org/uniprot/HDA3_YEAST HDA3_YEAST] Required for activity of HDA1 histone deacetylase complex. The HDA1 histone deacetylase complex is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.<ref>PMID:8663039</ref> <ref>PMID:11287668</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Huber, R]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Lee, J H]]
[[Category: Huber R]]
[[Category: Maskos, K]]
[[Category: Lee JH]]
[[Category: Chromatin regulator]]
[[Category: Maskos K]]
[[Category: Coiled coil]]
[[Category: Nucleus]]
[[Category: Reca-like domain]]
[[Category: Repressor]]
[[Category: Swi2/snf2 helical domain]]
[[Category: Transcription]]
[[Category: Transcription regulation]]