3lq0: Difference between revisions

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<StructureSection load='3lq0' size='340' side='right'caption='[[3lq0]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='3lq0' size='340' side='right'caption='[[3lq0]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3lq0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Astas Astas]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LQ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LQ0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3lq0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Astacus_astacus Astacus astacus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LQ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LQ0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ast|1ast]], [[1iaa|1iaa]], [[1iab|1iab]], [[1iac|1iac]], [[1iad|1iad]], [[1iae|1iae]], [[1qji|1qji]], [[1qjj|1qjj]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Astacin Astacin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.21 3.4.24.21] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lq0 OCA], [https://pdbe.org/3lq0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lq0 RCSB], [https://www.ebi.ac.uk/pdbsum/3lq0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lq0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lq0 OCA], [https://pdbe.org/3lq0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lq0 RCSB], [https://www.ebi.ac.uk/pdbsum/3lq0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lq0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ASTA_ASTAS ASTA_ASTAS]] This protease prefers to cleave in front of small aliphatic residues (P1'). The presence of Lys or Arg in the P1 and P2 position yields high-turnover substrates. In the P3 position the enzyme prefers Pro > Val > Leu > Ala > Gly.  
[https://www.uniprot.org/uniprot/ASTA_ASTAS ASTA_ASTAS] This protease prefers to cleave in front of small aliphatic residues (P1'). The presence of Lys or Arg in the P1 and P2 position yields high-turnover substrates. In the P3 position the enzyme prefers Pro > Val > Leu > Ala > Gly.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lq/3lq0_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lq/3lq0_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Proteinase|Proteinase]]
*[[Proteinase 3D structures|Proteinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Astacin]]
[[Category: Astacus astacus]]
[[Category: Astas]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bissdorf, S]]
[[Category: Bissdorf S]]
[[Category: Gomis-Ruth, F X]]
[[Category: Gomis-Ruth FX]]
[[Category: Guevara, T]]
[[Category: Guevara T]]
[[Category: Kappelhoff, R]]
[[Category: Kappelhoff R]]
[[Category: Stocker, W]]
[[Category: Stocker W]]
[[Category: Yiallouros, I]]
[[Category: Yiallouros I]]
[[Category: Disulfide bond]]
[[Category: Hydrolase]]
[[Category: Metal-binding]]
[[Category: Metallopeptidase]]
[[Category: Metalloprotease]]
[[Category: Proenzyme]]
[[Category: Protease]]
[[Category: Zymogen]]
[[Category: Zymogen activation]]
Retrieved from "https://proteopedia.org/3lq0"