1znu: Difference between revisions
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==Structure of cyclotide Kalata B1 in DPC micelles solution== | ==Structure of cyclotide Kalata B1 in DPC micelles solution== | ||
<StructureSection load='1znu' size='340' side='right'caption='[[1znu | <StructureSection load='1znu' size='340' side='right'caption='[[1znu]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1znu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oldenlandia_affinis Oldenlandia affinis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZNU FirstGlance]. <br> | <table><tr><td colspan='2'>[[1znu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oldenlandia_affinis Oldenlandia affinis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZNU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZNU FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1znu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1znu OCA], [https://pdbe.org/1znu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1znu RCSB], [https://www.ebi.ac.uk/pdbsum/1znu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1znu ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1znu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1znu OCA], [https://pdbe.org/1znu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1znu RCSB], [https://www.ebi.ac.uk/pdbsum/1znu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1znu ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/KAB1_OLDAF KAB1_OLDAF] Probably participates in a plant defense mechanism. Has antibiotic activity. Has a diuretic effect. Has a uterotonic effect in humans. Active against the Gram-positive S.aureus with a minimum inhibition concentration of approximately 0.2 microM. Relatively ineffective against Gram-negative bacteria such as E.coli and P.aeruginosa. Inhibitory effect on the growth and development of larvae from H.punctigera. The unmodified form has hemolytic activity, the oxidized form lacks hemolytic activity. If the protein is linearized, hemolytic activity is lost.<ref>PMID:17534989</ref> <ref>PMID:12779323</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Oldenlandia affinis]] | [[Category: Oldenlandia affinis]] | ||
[[Category: Arseniev | [[Category: Arseniev AS]] | ||
[[Category: Nadezhdin | [[Category: Nadezhdin KD]] | ||
[[Category: Shenkarev | [[Category: Shenkarev ZO]] | ||
[[Category: Skjeldal | [[Category: Skjeldal L]] | ||
[[Category: Sobol | [[Category: Sobol AG]] | ||
[[Category: Sobol | [[Category: Sobol VA]] | ||