Neurotransmitters: Difference between revisions
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**Noradrenaline | **Noradrenaline | ||
**Carmoterol, see [[2y02]]. | **Carmoterol, see [[2y02]]. | ||
**Salbutamol (Albuterol in USA), [[2y04]]. | **[[Salbutamol]] (Albuterol in USA), [[2y04]]. | ||
*Beta blockers: | *Beta blockers: | ||
**Metoprolol | **Metoprolol | ||
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*G<sub>s</sub>: adenylate cyclase activated, cAMP up. For G<sub>s</sub> see [[Beta2 adrenergic receptor-Gs protein complex updated]]. | *G<sub>s</sub>: adenylate cyclase activated, cAMP up. For G<sub>s</sub> see [[Beta2 adrenergic receptor-Gs protein complex updated]]. | ||
β2-adrenergic agonists: | β2-adrenergic agonists: | ||
**Salbutamol (Albuterol in USA) | **[[Salbutamol]] (Albuterol in USA) | ||
**Bitolterol mesylate | **Bitolterol mesylate | ||
**Formoterol | **[[Formoterol]] | ||
**Isoprenaline | **Isoprenaline | ||
**Levalbuterol | **Levalbuterol | ||
**Metaproterenol | **Metaproterenol | ||
**Salmeterol | **[[Salmeterol]] | ||
**Terbutaline | **Terbutaline | ||
**Ritodrine | **Ritodrine | ||
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=GABA= | =GABA= | ||
==GABA receptors== | ==GABA receptors== | ||
'''GABA''' (i.e. gamma-aminobutyric acid) is the primary inhibitory neurotransmitter of the vertebrate central nervous system. GABA can bind one of two different receptor proteins, each using a discrete mechanism to elicit a cellular response. Upon binding with GABA, '''GABAB receptors''' (metabotropic) utilize a second messenger amplification pathway that ultimately results in an inhibitory signal for neuronal transmission. This pathway for signal transmission differs from | '''GABA''' (i.e. gamma-aminobutyric acid) is the primary inhibitory neurotransmitter of the vertebrate central nervous system. GABA can bind one of two different receptor proteins, each using a discrete mechanism to elicit a cellular response. Upon binding with GABA, '''GABAB receptors''' (metabotropic) utilize a second messenger amplification pathway that ultimately results in an inhibitory signal for neuronal transmission. This pathway for signal transmission differs from [[GABAA receptors]] (ionotropic), which are considered ligand-gated ion channels as the binding of GABA results in the opening of ion channels leading to the inhibition of a neuronal signal. | ||
<scene name='82/829381/Cv/9'>GABA bound to the GABAB receptor</scene> (PDB code [[4ms3]]). | <scene name='82/829381/Cv/9'>GABA bound to the GABAB receptor</scene> (PDB code [[4ms3]]). | ||
*[[GABA receptor]] | *[[GABA receptor]] | ||
