2cn2: Difference between revisions

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<StructureSection load='2cn2' size='340' side='right'caption='[[2cn2]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='2cn2' size='340' side='right'caption='[[2cn2]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cn2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"ruminiclostridium_thermocellum"_yutin_and_galperin_2013 "ruminiclostridium thermocellum" yutin and galperin 2013]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CN2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cn2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus Acetivibrio thermocellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CN2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CN2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2cn3|2cn3]]</div></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Xyloglucan-specific_endo-beta-1,4-glucanase Xyloglucan-specific endo-beta-1,4-glucanase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.151 3.2.1.151] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cn2 OCA], [https://pdbe.org/2cn2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cn2 RCSB], [https://www.ebi.ac.uk/pdbsum/2cn2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cn2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cn2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cn2 OCA], [https://pdbe.org/2cn2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cn2 RCSB], [https://www.ebi.ac.uk/pdbsum/2cn2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cn2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/XG74_CLOTM XG74_CLOTM]] Hydrolyzes the glucosidic bonds of unbranched Glc residues in tamarind seed xyloglucan, producing XXXG, XLXG, XXLG and XLLG. Has low activity on carboxymethylcellulose, lichenan,hydroxyethylcellulose and glucuronoxylan, and no activity on xylan, polygalaturonic acid, wheat arabinoxylan, rhamnogalacturan, curdlan, laminarin, galactomannan, galactan, arabinan and pachyman or amorphous cellulose.<ref>PMID:16207921</ref> <ref>PMID:16772298</ref>
[https://www.uniprot.org/uniprot/XG74_ACETH XG74_ACETH] Hydrolyzes the glucosidic bonds of unbranched Glc residues in tamarind seed xyloglucan, producing XXXG, XLXG, XXLG and XLLG. Has low activity on carboxymethylcellulose, lichenan,hydroxyethylcellulose and glucuronoxylan, and no activity on xylan, polygalaturonic acid, wheat arabinoxylan, rhamnogalacturan, curdlan, laminarin, galactomannan, galactan, arabinan and pachyman or amorphous cellulose.<ref>PMID:16207921</ref> <ref>PMID:16772298</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cn/2cn2_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cn/2cn2_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ruminiclostridium thermocellum yutin and galperin 2013]]
[[Category: Acetivibrio thermocellus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Xyloglucan-specific endo-beta-1,4-glucanase]]
[[Category: Baumann MJ]]
[[Category: Baumann, M J]]
[[Category: Brumer H]]
[[Category: Brumer, H]]
[[Category: Davies GJ]]
[[Category: Davies, G J]]
[[Category: Ferreira LMA]]
[[Category: Ferreira, L M.A]]
[[Category: Fontes CMGA]]
[[Category: Fontes, C M.G A]]
[[Category: Guerreiro CI]]
[[Category: Guerreiro, C I]]
[[Category: Martinez-Fleites C]]
[[Category: Martinez-Fleites, C]]
[[Category: Prates JAM]]
[[Category: Prates, J A.M]]
[[Category: Taylor EJ]]
[[Category: Taylor, E J]]
[[Category: Gh74 family]]
[[Category: Glycosylhydrolase]]
[[Category: Hydrolase]]
[[Category: Xyloglucanase]]