2cw8: Difference between revisions

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<StructureSection load='2cw8' size='340' side='right'caption='[[2cw8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2cw8' size='340' side='right'caption='[[2cw8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cw8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_kodakaraensis_(strain_kod1) Pyrococcus kodakaraensis (strain kod1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CW8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CW8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cw8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_kodakarensis_KOD1 Thermococcus kodakarensis KOD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CW8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CW8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2cw7|2cw7]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cw8 OCA], [https://pdbe.org/2cw8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cw8 RCSB], [https://www.ebi.ac.uk/pdbsum/2cw8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cw8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cw8 OCA], [https://pdbe.org/2cw8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cw8 RCSB], [https://www.ebi.ac.uk/pdbsum/2cw8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cw8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/DPOL_PYRKO DPOL_PYRKO]] Intein encoded endonucleases are thought to mediate intein mobility by site-specific recombination initiated by endonuclease cleavage at the "homing site" in gene that lack the intein. PI-PkoI recognizes 5'-GATTTAGATCCCTGTACC-3' and PI-PkoII recognizes 5'-CAGCTACTACGGTTAC-3'.  
[https://www.uniprot.org/uniprot/DPOL_THEKO DPOL_THEKO] Intein encoded endonucleases are thought to mediate intein mobility by site-specific recombination initiated by endonuclease cleavage at the "homing site" in gene that lack the intein. PI-PkoI recognizes 5'-GATTTAGATCCCTGTACC-3' and PI-PkoII recognizes 5'-CAGCTACTACGGTTAC-3'.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Fujiwara, S]]
[[Category: Thermococcus kodakarensis KOD1]]
[[Category: Hashimoto, H]]
[[Category: Fujiwara S]]
[[Category: Imanaka, T]]
[[Category: Hashimoto H]]
[[Category: Inoue, T]]
[[Category: Imanaka T]]
[[Category: Kai, Y]]
[[Category: Inoue T]]
[[Category: Matsumura, H]]
[[Category: Kai Y]]
[[Category: Nishioka, M]]
[[Category: Matsumura H]]
[[Category: Takagi, M]]
[[Category: Nishioka M]]
[[Category: Takahashi, H]]
[[Category: Takagi M]]
[[Category: Hydrolase]]
[[Category: Takahashi H]]

Latest revision as of 11:31, 22 May 2024

Crystal structure of intein homing endonuclease II

2cw8, resolution 2.50Å

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