2zp8: Difference between revisions

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<StructureSection load='2zp8' size='340' side='right'caption='[[2zp8]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='2zp8' size='340' side='right'caption='[[2zp8]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zp8]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835] and [https://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZP8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zp8]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZP8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zp9|2zp9]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mtrB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 ATCC 12980]), rtpA, yczA, BSU02530 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zp8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zp8 OCA], [https://pdbe.org/2zp8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zp8 RCSB], [https://www.ebi.ac.uk/pdbsum/2zp8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zp8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zp8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zp8 OCA], [https://pdbe.org/2zp8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zp8 RCSB], [https://www.ebi.ac.uk/pdbsum/2zp8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zp8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RTPA_BACSU RTPA_BACSU]] By forming a complex with tryptophan-activated TRAP, and masking its RNA binding site, it inhibits TRAP's RNA binding ability, thereby abolishing TRAP regulation of gene expression, leading to antitermination and increased trp operon expression. AT acts by competing with messenger RNA for the RNA binding domain of TRAP.
[https://www.uniprot.org/uniprot/MTRB_GEOSE MTRB_GEOSE]  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Vibrio subtilis ehrenberg 1835]]
[[Category: Bacillus subtilis]]
[[Category: Atcc 12980]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Akashi, S]]
[[Category: Akashi S]]
[[Category: Heddle, J G]]
[[Category: Heddle JG]]
[[Category: Park, S Y]]
[[Category: Park SY]]
[[Category: Tame, J R.H]]
[[Category: Tame JRH]]
[[Category: Unzai, S]]
[[Category: Unzai S]]
[[Category: Watanabe, M]]
[[Category: Watanabe M]]
[[Category: Protein-protein complex]]
[[Category: Rna binding protein-transcription complex]]
[[Category: Rna-binding]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
Retrieved from "https://proteopedia.org/2zp8"