7wih: Difference between revisions
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==Cryo-EM structure of LY2794193-bound mGlu3== | |||
<StructureSection load='7wih' size='340' side='right'caption='[[7wih]], [[Resolution|resolution]] 3.68Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7wih]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WIH FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CWY:(1S,2S,4S,5R,6S)-2-amino-4-[(3-methoxybenzene-1-carbonyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic+acid'>CWY</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wih OCA], [https://pdbe.org/7wih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wih RCSB], [https://www.ebi.ac.uk/pdbsum/7wih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wih ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: Lin | [[https://www.uniprot.org/uniprot/GRM3_HUMAN GRM3_HUMAN]] G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.<ref>PMID:8840013</ref> | ||
[[Category: Ling | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Fang W]] | ||
[[Category: | [[Category: Lin L]] | ||
[[Category: | [[Category: Ling SL]] | ||
[[Category: | [[Category: Liu JF]] | ||
[[Category: | [[Category: Liu P]] | ||
[[Category: Pan S]] | |||
[[Category: Pin JP]] | |||
[[Category: Rondard P]] | |||
[[Category: Sun WJ]] | |||
[[Category: Tian CL]] | |||
[[Category: Wang XM]] | |||
[[Category: Xu CJ]] | |||
[[Category: Yang F]] | |||
[[Category: Zhou YX]] | |||
Latest revision as of 05:34, 8 September 2022
Cryo-EM structure of LY2794193-bound mGlu3
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