6pl0: Difference between revisions

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<StructureSection load='6pl0' size='340' side='right'caption='[[6pl0]], [[Resolution|resolution]] 2.96&Aring;' scene=''>
<StructureSection load='6pl0' size='340' side='right'caption='[[6pl0]], [[Resolution|resolution]] 2.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6pl0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanc8 Xanc8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PL0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PL0 FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PL0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PL0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BLA:BILIVERDINE+IX+ALPHA'>BLA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.96&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5akp|5akp]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BLA:BILIVERDINE+IX+ALPHA'>BLA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bphP, XC_4241 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=314565 XANC8])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pl0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pl0 OCA], [https://pdbe.org/6pl0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pl0 RCSB], [https://www.ebi.ac.uk/pdbsum/6pl0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pl0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pl0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pl0 OCA], [https://pdbe.org/6pl0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pl0 RCSB], [https://www.ebi.ac.uk/pdbsum/6pl0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pl0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/BPHY_XANC8 BPHY_XANC8]] Photoreceptor which exists in two forms that are reversibly interconvertible by light: far-red light (733 nm) converts protein to the red-absorbing (Pr) form, while red light (630 nm) partly converts the protein to the far-red-absorbing (Pfr) form (PubMed:27107635). Regulates virulence of X.campestris pv. campestris on its host plants, perhaps by fine-tuning expression to ambient light levels and/or spatial cues (PubMed:27621284). The Pr form may sense light and partially inhibit virulence; in the dark (Pfr form) biofilm and xanathan production rise and bacteria are more virulent (PubMed:27621284). Strains overexpressing this protein have significantly decreased amounts of extracellular beta-1,4-endoglucanase, produce less xanthin and have decreased transcription of genes involved in virulence such as endoglucanases, type 2 secretion systems, xanthan production and flagellar-dependent motility (PubMed:27621284).<ref>PMID:27107635</ref> <ref>PMID:27621284</ref> <ref>PMID:27621284</ref> 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
[Figure: see text].
Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level.,Otero LH, Foscaldi S, Antelo GT, Rosano GL, Sirigu S, Klinke S, Defelipe LA, Sanchez-Lamas M, Battocchio G, Conforte V, Vojnov AA, Chavas LMG, Goldbaum FA, Mroginski MA, Rinaldi J, Bonomi HR Sci Adv. 2021 Nov 26;7(48):eabh1097. doi: 10.1126/sciadv.abh1097. Epub 2021 Nov, 24. PMID:34818032<ref>PMID:34818032</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 6pl0" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Xanc8]]
[[Category: Bonomi HR]]
[[Category: Bonomi, H R]]
[[Category: Chavas L]]
[[Category: Chavas, L]]
[[Category: Goldbaum F]]
[[Category: Goldbaum, F]]
[[Category: Klinke S]]
[[Category: Klinke, S]]
[[Category: Otero LH]]
[[Category: Otero, L H]]
[[Category: Rinaldi J]]
[[Category: Rinaldi, J]]
[[Category: Sirigu S]]
[[Category: Sirigu, S]]
[[Category: Bacterial protein]]
[[Category: Photoreceptor]]
[[Category: Photosensor]]
[[Category: Phytochrome]]
[[Category: Phytopathogen]]
[[Category: Red/far-red light]]
[[Category: Signal transduction]]
[[Category: Signaling protein]]
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