Sandbox Test M: Difference between revisions
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==AlphaFold2 Model of Sars-CoV-2 Protein M== | ==AlphaFold2 Model of Sars-CoV-2 Protein M== | ||
<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='90/902730/ | <StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='90/902730/Sars-cov-2_protein_m/3'> | ||
{{Theoretical_model}} {{Template:ModelConfidence}} | {{Theoretical_model}} {{Template:ModelConfidence}} | ||
= | To the right is an '''[[AlphaFold]]2''' 3D model of SARS CoV-2 Protein (UniProt ID: QHD43419) color coded by the pLDDT scores. It corresponds to the highest ranked model in terms of the pLDDT confidence scores, ''i.e.'', model 4<ref name="MIT_ColabFold"> MIT ColabFold https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/beta/AlphaFold2_advanced.ipynb </ref>. | ||
== Function == | == Function == | ||
'''Protein M''' | '''Protein M''' | ||
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.<ref>[https://zhanglab.ccmb.med.umich.edu/COVID-19/ Modeling of the SARS-COV-2 Genome]</ref><ref>pmid 32200634</ref> | Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.<ref>[https://zhanglab.ccmb.med.umich.edu/COVID-19/ Modeling of the SARS-COV-2 Genome]</ref><ref>pmid 32200634</ref>] | ||
== Disease == | == Disease == | ||
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== Structural highlights == | == Structural highlights == | ||
[[Image:SARSCoV2_protein_M_250.gif|250px|left|thumb|'''Morph''' of the top 5 ranked [[AlphaFold]]2 models of '''SARS-CoV-2 Protein M''', ''rainbow'' color coded N-C<ref name="MIT_ColabFold"/>.]] | |||
== See also == | == See also == | ||
Latest revision as of 17:45, 3 February 2022
AlphaFold2 Model of Sars-CoV-2 Protein M
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