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==Human STING bound to both cGAMP and 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide (Compound 53)==
==Human STING bound to both cGAMP and 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide (Compound 53)==
<StructureSection load='7sii' size='340' side='right'caption='[[7sii]]' scene=''>
<StructureSection load='7sii' size='340' side='right'caption='[[7sii]], [[Resolution|resolution]] 3.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SII FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SII FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sii OCA], [https://pdbe.org/7sii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sii RCSB], [https://www.ebi.ac.uk/pdbsum/7sii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sii ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.45&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1SY:CGAMP'>1SY</scene>, <scene name='pdbligand=9IM:1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide'>9IM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sii OCA], [https://pdbe.org/7sii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sii RCSB], [https://www.ebi.ac.uk/pdbsum/7sii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sii ProSAT]</span></td></tr>
</table>
</table>
==See Also==
*[[Stimulator of interferon genes protein 3D structures|Stimulator of interferon genes protein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Latest revision as of 05:51, 5 June 2024

Human STING bound to both cGAMP and 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide (Compound 53)

7sii, resolution 3.45Å

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