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==Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 14b==
==Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 14b==
<StructureSection load='7tq7' size='340' side='right'caption='[[7tq7]]' scene=''>
<StructureSection load='7tq7' size='340' side='right'caption='[[7tq7]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TQ7 FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TQ7 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tq7 OCA], [https://pdbe.org/7tq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tq7 RCSB], [https://www.ebi.ac.uk/pdbsum/7tq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tq7 ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IRR:N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-N~2~-({[(1R,2R)-2-propylcyclopropyl]methoxy}carbonyl)-L-leucinamide'>IRR</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tq7 OCA], [https://pdbe.org/7tq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tq7 RCSB], [https://www.ebi.ac.uk/pdbsum/7tq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tq7 ProSAT]</span></td></tr>
</table>
</table>
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Latest revision as of 06:49, 21 November 2024

Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 14b

7tq7, resolution 1.70Å

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