6ia3: Difference between revisions

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<StructureSection load='6ia3' size='340' side='right'caption='[[6ia3]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
<StructureSection load='6ia3' size='340' side='right'caption='[[6ia3]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6ia3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspfl Aspfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IA3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IA3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6ia3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_flavus Aspergillus flavus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IA3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IA3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AR:ARGON'>AR</scene>, <scene name='pdbligand=AZA:8-AZAXANTHINE'>AZA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=AR:ARGON'>AR</scene>, <scene name='pdbligand=AZA:8-AZAXANTHINE'>AZA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xt4|1xt4]], [[2ic0|2ic0]], [[3obp|3obp]], [[3plm|3plm]], [[4op6|4op6]], [[4op9|4op9]], [[5frc|5frc]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">uaZ, uox ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5059 ASPFL])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Factor_independent_urate_hydroxylase Factor independent urate hydroxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.3.3 1.7.3.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ia3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ia3 OCA], [https://pdbe.org/6ia3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ia3 RCSB], [https://www.ebi.ac.uk/pdbsum/6ia3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ia3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ia3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ia3 OCA], [https://pdbe.org/6ia3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ia3 RCSB], [https://www.ebi.ac.uk/pdbsum/6ia3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ia3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/URIC_ASPFL URIC_ASPFL]] Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.  
[https://www.uniprot.org/uniprot/URIC_ASPFL URIC_ASPFL] Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.


==See Also==
==See Also==
*[[Urate Oxidase|Urate Oxidase]]
*[[Urate oxidase 3D structures|Urate oxidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aspfl]]
[[Category: Aspergillus flavus]]
[[Category: Factor independent urate hydroxylase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Carpentier, P]]
[[Category: Carpentier P]]
[[Category: Prange, T]]
[[Category: Colloc'h N]]
[[Category: H, N Colloc]]
[[Category: Prange T]]
[[Category: Argon]]
[[Category: Aspergillus flavus]]
[[Category: High pressure]]
[[Category: Homotetramer]]
[[Category: Oxidoreductase]]
[[Category: Purine metabolism]]

Latest revision as of 11:50, 24 January 2024

urate oxidase under 220 bar (22 MPa) of argon

6ia3, resolution 1.69Å

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