1k5o: Difference between revisions

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==CPI-17(35-120) deletion mutant==
==CPI-17(35-120) deletion mutant==
<StructureSection load='1k5o' size='340' side='right'caption='[[1k5o]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
<StructureSection load='1k5o' size='340' side='right'caption='[[1k5o]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1k5o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pig Pig]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K5O FirstGlance]. <br>
<table><tr><td colspan='2'>[[1k5o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K5O FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">porcine aorta ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 PIG])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k5o OCA], [https://pdbe.org/1k5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k5o RCSB], [https://www.ebi.ac.uk/pdbsum/1k5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k5o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k5o OCA], [https://pdbe.org/1k5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k5o RCSB], [https://www.ebi.ac.uk/pdbsum/1k5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k5o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PP14A_PIG PP14A_PIG]] Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.<ref>PMID:9237662</ref> <ref>PMID:8720121</ref> <ref>PMID:10924361</ref> <ref>PMID:10869555</ref>
[https://www.uniprot.org/uniprot/PP14A_PIG PP14A_PIG] Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.<ref>PMID:9237662</ref> <ref>PMID:8720121</ref> <ref>PMID:10924361</ref> <ref>PMID:10869555</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pig]]
[[Category: Sus scrofa]]
[[Category: Brautigan, D]]
[[Category: Brautigan D]]
[[Category: Eto, M]]
[[Category: Eto M]]
[[Category: Hayano, T]]
[[Category: Hayano T]]
[[Category: Hayashi, Y]]
[[Category: Hayashi Y]]
[[Category: Kainosho, M]]
[[Category: Kainosho M]]
[[Category: Kariya, E]]
[[Category: Kariya E]]
[[Category: Ohki, S]]
[[Category: Ohki S]]
[[Category: Yazawa, M]]
[[Category: Yazawa M]]
[[Category: Mlcp-inhibitor]]
[[Category: Phosphorylation]]
[[Category: Pp1-inhibitor]]
[[Category: Protein binding]]
Retrieved from "https://proteopedia.org/1k5o"