7yz8: Difference between revisions
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==Triclinic crystal structure of YTHDF1 YTH domain (544AVV546 mutant)== | |||
<StructureSection load='7yz8' size='340' side='right'caption='[[7yz8]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7yz8]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YZ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YZ8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yz8 OCA], [https://pdbe.org/7yz8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yz8 RCSB], [https://www.ebi.ac.uk/pdbsum/7yz8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yz8 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[https://www.uniprot.org/uniprot/YTHD1_HUMAN YTHD1_HUMAN] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability.<ref>PMID:24284625</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Cazzanelli G]] | |||
[[Category: Dalle Vedove A]] | |||
[[Category: Lolli G]] | |||
Latest revision as of 08:01, 7 February 2024
Triclinic crystal structure of YTHDF1 YTH domain (544AVV546 mutant)
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