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==Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta==
==Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta==
<StructureSection load='1r79' size='340' side='right'caption='[[1r79]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1r79' size='340' side='right'caption='[[1r79]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1r79]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R79 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1r79]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R79 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KAZUSA cDNA ha00914 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r79 OCA], [https://pdbe.org/1r79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r79 RCSB], [https://www.ebi.ac.uk/pdbsum/1r79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r79 ProSAT], [https://www.topsan.org/Proteins/RSGI/1r79 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r79 OCA], [https://pdbe.org/1r79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r79 RCSB], [https://www.ebi.ac.uk/pdbsum/1r79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r79 ProSAT], [https://www.topsan.org/Proteins/RSGI/1r79 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/DGKD_HUMAN DGKD_HUMAN]] May function as signaling molecule.<ref>PMID:17880279</ref>  Isoform 2 may be involved in cell growth and tumorigenesis. Involved in clathrin-dependent endocytosis.<ref>PMID:17880279</ref>
[https://www.uniprot.org/uniprot/DGKD_HUMAN DGKD_HUMAN] May function as signaling molecule.<ref>PMID:17880279</ref>  Isoform 2 may be involved in cell growth and tumorigenesis. Involved in clathrin-dependent endocytosis.<ref>PMID:17880279</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Diacylglycerol kinase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Inoue, M]]
[[Category: Inoue M]]
[[Category: Kigawa, T]]
[[Category: Kigawa T]]
[[Category: Koshiba, S]]
[[Category: Koshiba S]]
[[Category: Miyamoto, K]]
[[Category: Miyamoto K]]
[[Category: Structural genomic]]
[[Category: Tomizawa T]]
[[Category: Tomizawa, T]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: C1 domain]]
[[Category: Cystein-rich zinc binding domain]]
[[Category: Diacylglycerol kinase delta]]
[[Category: Rsgi]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/1r79"