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==Solution structure of the zinc finger domain of TFIIE alpha==
==Solution structure of the zinc finger domain of TFIIE alpha==
<StructureSection load='1vd4' size='340' side='right'caption='[[1vd4]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1vd4' size='340' side='right'caption='[[1vd4]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1vd4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VD4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VD4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1vd4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VD4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VD4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1d8j|1d8j]], [[1d8k|1d8k]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GTF2E1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vd4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vd4 OCA], [https://pdbe.org/1vd4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vd4 RCSB], [https://www.ebi.ac.uk/pdbsum/1vd4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vd4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vd4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vd4 OCA], [https://pdbe.org/1vd4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vd4 RCSB], [https://www.ebi.ac.uk/pdbsum/1vd4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vd4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/T2EA_HUMAN T2EA_HUMAN]] Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.  
[https://www.uniprot.org/uniprot/T2EA_HUMAN T2EA_HUMAN] Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arai, Y]]
[[Category: Arai Y]]
[[Category: Hanaoka, F]]
[[Category: Hanaoka F]]
[[Category: Nagadoi, A]]
[[Category: Nagadoi A]]
[[Category: Nishimura, Y]]
[[Category: Nishimura Y]]
[[Category: Ohkuma, Y]]
[[Category: Ohkuma Y]]
[[Category: Okamura, H]]
[[Category: Okamura H]]
[[Category: Okuda, M]]
[[Category: Okuda M]]
[[Category: Satoh, M]]
[[Category: Satoh M]]
[[Category: Tanaka, A]]
[[Category: Tanaka A]]
[[Category: Transcription]]
[[Category: Zinc finger]]
Retrieved from "https://proteopedia.org/1vd4"