1wg7: Difference between revisions
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==Solution structure of pleckstrin homology domain from human KIAA1058 protein== | ==Solution structure of pleckstrin homology domain from human KIAA1058 protein== | ||
<StructureSection load='1wg7' size='340' side='right'caption='[[1wg7 | <StructureSection load='1wg7' size='340' side='right'caption='[[1wg7]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1wg7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1wg7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WG7 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wg7 OCA], [https://pdbe.org/1wg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wg7 RCSB], [https://www.ebi.ac.uk/pdbsum/1wg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wg7 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wg7 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wg7 OCA], [https://pdbe.org/1wg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wg7 RCSB], [https://www.ebi.ac.uk/pdbsum/1wg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wg7 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wg7 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/DOCK9_HUMAN DOCK9_HUMAN] Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Overexpression induces filopodia formation.<ref>PMID:12172552</ref> <ref>PMID:19745154</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Hayashi | [[Category: Hayashi F]] | ||
[[Category: Inoue | [[Category: Inoue K]] | ||
[[Category: Suetake T]] | |||
[[Category: Suetake | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||
Latest revision as of 13:37, 9 May 2024
Solution structure of pleckstrin homology domain from human KIAA1058 protein
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