1x4m: Difference between revisions
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==Solution structure of KH domain in Far upstream element binding protein 1== | ==Solution structure of KH domain in Far upstream element binding protein 1== | ||
<StructureSection load='1x4m' size='340' side='right'caption='[[1x4m | <StructureSection load='1x4m' size='340' side='right'caption='[[1x4m]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1x4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1x4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X4M FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x4m OCA], [https://pdbe.org/1x4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x4m RCSB], [https://www.ebi.ac.uk/pdbsum/1x4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x4m ProSAT], [https://www.topsan.org/Proteins/RSGI/1x4m TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x4m OCA], [https://pdbe.org/1x4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x4m RCSB], [https://www.ebi.ac.uk/pdbsum/1x4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x4m ProSAT], [https://www.topsan.org/Proteins/RSGI/1x4m TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/FUBP1_MOUSE FUBP1_MOUSE] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: He | [[Category: He F]] | ||
[[Category: Inoue | [[Category: Inoue M]] | ||
[[Category: Kigawa | [[Category: Kigawa T]] | ||
[[Category: Muto | [[Category: Muto Y]] | ||
[[Category: Shirouzu M]] | |||
[[Category: Shirouzu | [[Category: Terada T]] | ||
[[Category: Terada | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||