3fm0: Difference between revisions
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<StructureSection load='3fm0' size='340' side='right'caption='[[3fm0]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='3fm0' size='340' side='right'caption='[[3fm0]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3fm0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3fm0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FM0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FM0 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fm0 OCA], [https://pdbe.org/3fm0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fm0 RCSB], [https://www.ebi.ac.uk/pdbsum/3fm0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fm0 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fm0 OCA], [https://pdbe.org/3fm0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fm0 RCSB], [https://www.ebi.ac.uk/pdbsum/3fm0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fm0 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CIAO1_HUMAN CIAO1_HUMAN] Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.<ref>PMID:17937914</ref> <ref>PMID:20797633</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Bochkarev | [[Category: Bochkarev A]] | ||
[[Category: Bountra | [[Category: Bountra C]] | ||
[[Category: Cossar | [[Category: Cossar D]] | ||
[[Category: Crombet | [[Category: Crombet L]] | ||
[[Category: Dong | [[Category: Dong A]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Min | [[Category: Min J]] | ||
[[Category: Ouyang | [[Category: Ouyang H]] | ||
[[Category: Ravichandran | [[Category: Ravichandran M]] | ||
[[Category: Weigelt J]] | |||
[[Category: Weigelt | |||
