7x4v: Difference between revisions

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'''Unreleased structure'''


The entry 7x4v is ON HOLD
==Crystal structure of Rhodostomin ARGDDP mutant==
 
<StructureSection load='7x4v' size='340' side='right'caption='[[7x4v]], [[Resolution|resolution]] 1.38&Aring;' scene=''>
Authors: Chang, Y.T., Chuang, W.J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7x4v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X4V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X4V FirstGlance]. <br>
Description: Crystal structure of Rhodostomin ARGDDP mutant
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.38&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x4v OCA], [https://pdbe.org/7x4v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x4v RCSB], [https://www.ebi.ac.uk/pdbsum/7x4v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x4v ProSAT]</span></td></tr>
[[Category: Chang, Y.T]]
</table>
[[Category: Chuang, W.J]]
== Function ==
[https://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity).  Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
__TOC__
</StructureSection>
[[Category: Calloselasma rhodostoma]]
[[Category: Large Structures]]
[[Category: Chang YT]]
[[Category: Chuang WJ]]
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